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Natural Remedies for LPR: What Actually Works (and What Doesn’t)

natural remedies for lpr

There’s no shortage of natural remedies recommended for LPR (silent reflux). The problem is that most of them were developed for classic GERD — heartburn and acid in the oesophagus — not for the very different problem of pepsin reaching the throat. What soothes heartburn doesn’t necessarily address what’s actually driving your LPR symptoms.

I want to be honest in this article. Some natural remedies genuinely help LPR. Some are useful for symptom relief but don’t address the root cause. And some are a waste of money. I’ll tell you which is which, what I personally use, and why.

Key Takeaways:

  • The most effective natural treatments for LPR are a low acid diet and alkaline water — both directly address pepsin, the actual cause of LPR symptoms
  • Gaviscon Advance (UK version) is technically a medication but works through a natural alginate mechanism and is the closest thing to a “natural” barrier treatment available
  • Chamomile and marshmallow root tea provide genuine soothing relief for the throat — worth using alongside the main approach
  • Slippery elm and DGL licorice may help GERD symptoms but have limited specific evidence for LPR — useful additions but not central treatments
  • Apple cider vinegar, digestive enzymes and betaine HCL are not appropriate for LPR and can make it worse — avoid these despite what you may read elsewhere
  • Baking soda in water works as a quick short-term fix but is not suitable for daily use

Why LPR Is Different — and Why It Matters for Natural Remedies

Before getting into the remedies I want to explain why LPR requires a different approach to standard acid reflux. Most natural remedies you’ll find online are designed to neutralise stomach acid or soothe heartburn. For GERD — where acid in the oesophagus is the main problem — these make sense.

LPR is primarily driven by pepsin reaching the throat — not by acid levels in the stomach. Pepsin is the digestive enzyme that travels with gaseous reflux all the way up into the throat and voice box, where it damages tissue and causes most LPR symptoms. It can sit dormant in throat cells for 24 to 48 hours and be reactivated by anything acidic you eat or drink.

This means the most important natural interventions for LPR are those that either deactivate pepsin directly, stop it from being reactivated, or prevent it from reaching the throat in the first place. Remedies that simply neutralise acid in the stomach — without addressing pepsin — will give you limited results for LPR specifically.

You can read more about the pepsin mechanism in my guide to neutralising pepsin in the throat.


Tier 1: What Actually Treats LPR Naturally

1. Low Acid Diet — the most important natural treatment

The low acid diet is the single most effective natural treatment for LPR, and the evidence is clear on this. A 2017 study published in JAMA Otolaryngology (Zalvan et al.) compared a plant-based Mediterranean diet with alkaline water against PPI therapy in 184 LPR patients. The dietary approach produced at least equivalent results to PPIs — 63% of the dietary group achieved meaningful symptom reduction versus 54% in the PPI group.

The diet works on LPR from two angles. First, avoiding acidic foods and drinks stops dormant pepsin in the throat from being reactivated. Second, reducing the overall acid load in the stomach reduces the frequency and severity of the gaseous reflux events that send pepsin upward in the first place.

The threshold I recommend is avoiding anything with a pH below 5 — this is where pepsin reactivation becomes significant. The worst offenders are soft drinks, coffee, alcohol, citrus fruits and juices, tomatoes, vinegar, and carbonated water. For the complete food list see my LPR foods to avoid guide.

For a fully structured diet plan designed specifically for LPR, the Wipeout Diet Plan is the most comprehensive option I offer.

2. Alkaline Water — permanently deactivates pepsin

Alkaline water at pH 8.8 or above permanently and irreversibly deactivates pepsin on contact. This is one of the most directly useful natural interventions for LPR because it targets pepsin specifically — which is what’s actually causing your symptoms.

This is confirmed by Koufman and Johnston’s 2012 study in the Annals of Otology, Rhinology and Laryngology — pH 8.8 water instantly and irreversibly denatured human pepsin in laboratory testing. Regular water at pH 6.7 to 7.4 has no effect on pepsin whatsoever.

Make it your default drink throughout the day rather than an occasional supplement. First thing in the morning and after meals are particularly important times. A naturally alkaline spring water or quality alkaline filter pitcher at pH 9 or above is ideal. For everything you need to know about choosing and using it, see my alkaline water for LPR guide.

3. Alkaline Throat Spray — targets embedded pepsin directly

A simple homemade alkaline throat spray is one of the most underused tools for LPR. Mix half a teaspoon of baking soda into 250ml of alkaline water, put it in a small spray bottle, and spray 2 to 4 times into the back of the throat after meals, before bed and first thing in the morning.

This delivers alkaline contact directly to the upper throat and voice box area — where embedded pepsin may not be fully reached by simply drinking water. Dr Koufman recommends this specifically for people with persistent throat clearing, voice problems and globus. I’ve recommended it to many people through consultations and it works well alongside drinking alkaline water. More detail in my pepsin neutralisation guide.

4. Lifestyle changes — often overlooked but essential

Several lifestyle modifications have solid evidence behind them for reducing reflux and are genuinely natural interventions:

Don’t eat within 3 hours of bed. Lying down with a full stomach increases pressure on the lower oesophageal sphincter and dramatically increases the chance of gaseous reflux reaching the throat during sleep. This is one of the highest-impact changes you can make.

Keep portions moderate. Large meals overfill the stomach, increasing pressure on the valve above it. Smaller, more frequent meals are significantly better for LPR than two or three large ones.

Raise the head of your bed. Elevating by 15 to 20cm using bed risers under the legs — not just extra pillows, which can worsen things by bending the body — reduces nocturnal reflux. Most relevant for people with significant night-time symptoms.

Lose weight if relevant. Excess abdominal weight puts direct pressure on the stomach and lower oesophageal sphincter. For people who are overweight this is one of the most impactful long-term interventions available.


Tier 2: Useful for Symptom Relief

5. Marshmallow Root Tea — best for throat soothing

Marshmallow root (Althaea officinalis) is my top tea recommendation for LPR. Its high polysaccharide content forms a mucin-like protective layer over inflamed mucosa when it comes into contact with the throat and oesophagus lining. A 2025 systematic review published in Nutrients (PMC11944625) confirmed that the bioactive components in marshmallow root — including flavonoids — influence inflammatory pathways by reducing TNF-α and IL-6 levels, with genuine mucoprotective effects.

For LPR specifically, the coating effect on the throat is the main benefit — it doesn’t deactivate pepsin but it protects the irritated throat tissue from further damage while it heals. Steep one tablespoon of dried marshmallow root in hot water for 10 to 15 minutes, let it cool to a comfortable temperature before drinking, and have it 2 to 3 times daily. A cold infusion — soaking the root in room temperature water overnight — preserves more of the mucilage.

Important: don’t take marshmallow root at the same time as other medications — the mucilage can bind to them and reduce their absorption.

6. Chamomile Tea — anti-inflammatory and calming

Chamomile (Matricaria chamomilla) has genuine anti-inflammatory properties and can help settle the stomach and reduce irritation in the throat and oesophagus. The 2025 Nutrients review noted its therapeutic effect is due to anti-inflammatory and soothing properties that help alleviate oesophageal irritation and promote mucosal healing.

Dr Koufman rates chamomile as genuinely useful — specifically recommending it as a late evening option for people with LPR who get hungry before bed and need something safe that won’t trigger reflux. Brew 1 to 2 teaspoons of dried chamomile flowers in hot water for 5 minutes, let it cool before drinking. Avoid if you’re allergic to plants in the daisy family.

One thing to be aware of: don’t drink it too hot. Very hot liquids can irritate an already inflamed throat — let it cool to a comfortably warm temperature first. This applies to all teas.

7. Manuka Honey — soothing in small amounts

Regular honey is on the borderline pH-wise for LPR and I generally recommend avoiding it initially. Manuka honey is more alkaline than regular honey and has additional antibacterial and anti-inflammatory properties — a small amount (half to one teaspoon) stirred into marshmallow root or chamomile tea is a reasonable option once symptoms are stabilising. Don’t use it in the early, active stages of the diet when you’re being strict about pH.

8. Slippery Elm — modest evidence, mainly for GERD

Slippery elm (Ulmus rubra) contains mucilage that forms a protective gel coating over mucosal surfaces. The 2025 Nutrients review confirmed the coating mechanism is real and there is traditional use going back a long time. However, the honest assessment is that the evidence for slippery elm is primarily in GERD and general gastrointestinal irritation rather than specifically LPR. Dr Koufman’s view is that it’s “maybe helpful, but not worth the money” for LPR specifically.

I wouldn’t make it a priority spend. If you already have it or want to try it, mix one tablespoon of the powder in water and take after meals and before bed. Avoid taking it at the same time as medications. It’s safe and unlikely to cause harm — just don’t expect it to be transformative for LPR.


Tier 3: Limited Value for LPR

9. DGL Licorice — more relevant for GERD than LPR

DGL (deglycyrrhizinated licorice) — which has the compound that raises blood pressure removed — stimulates mucus production and can protect the oesophagus lining. There’s decent evidence for it in GERD and functional dyspepsia. A double-blind RCT (Raveendra et al.) showed significant improvement in dyspeptic symptoms with a standardised licorice extract versus placebo over 30 days.

For LPR the picture is less clear. Mucus production in the oesophagus helps with heartburn and oesophageal irritation — but LPR symptoms come from pepsin in the throat and voice box, which DGL doesn’t address directly. Koufman’s assessment is similar to slippery elm — possible benefit, but probably not worth spending significant money on for LPR specifically. If you want to try it, chewable tablets are the best form as they coat the oesophagus on the way down.

10. Baking Soda in Water — short-term fix only

Mixing half a teaspoon of baking soda in 150ml of water creates an alkaline mixture (around pH 8 to 9) that temporarily neutralises acid and can provide quick relief during a flare-up. It works — and it can be used in the throat spray I described above to raise the pH of the alkaline water further.

The problem with using it daily as a drink is the sodium content. Baking soda is very high in salt, and drinking it regularly adds a significant sodium load to your diet. It’s useful as a one-off rescue option when you have nothing else, but not something to rely on daily. For more see my baking soda for heartburn article.


What to Avoid — Natural Remedies That Can Make LPR Worse

Some commonly recommended natural remedies for acid reflux are actively problematic for LPR and should be avoided:

Apple cider vinegar. ACV has a pH of around 2 to 3 — highly acidic. Some people recommend it for GERD based on the theory that low stomach acid causes reflux. This is not relevant to LPR, and drinking something at pH 2 to 3 when you have pepsin sitting dormant in your throat is a recipe for reactivating it aggressively. Avoid entirely.

Digestive enzymes and betaine HCL. These are aimed at people with low stomach acid — the opposite of what most LPR patients have. Dr Koufman is explicit on this point: these supplements are counterproductive for reflux patients and should be avoided.

Peppermint tea. Menthol relaxes the lower oesophageal sphincter — the valve that keeps stomach contents from rising. For LPR this means peppermint can actively make reflux worse by loosening the barrier between the stomach and the oesophagus. Avoid despite its general reputation as a digestive remedy.

Citrus teas and drinks. Lemon tea, orange juice, anything marketed as a “detox” citrus drink — all highly acidic. These will reactivate pepsin and worsen symptoms regardless of any other purported health benefits.


The Complete Natural Treatment Stack for LPR

The most effective natural approach to LPR combines the Tier 1 treatments as your foundation, with the Tier 2 soothing remedies alongside them during the healing phase:

  • Foundation: Low acid diet (pH 5+ foods only) + alkaline water (pH 9+) as your main drink + alkaline throat spray after meals and before bed
  • Barrier protection: Gaviscon Advance (UK version) after every meal and before bed — this is technically a medication but works through natural alginate and is central to managing LPR
  • Symptom relief and throat healing: Marshmallow root tea 2 to 3 times daily + chamomile tea in the evening
  • Lifestyle: No eating within 3 hours of bed, moderate portions, head of bed elevated

Stick with this consistently for at least 4 to 6 weeks before evaluating. Most people start to notice genuine improvement within 2 weeks, with significant improvement by 6 to 8 weeks. For a personalised plan based on your specific symptoms, consider a private consultation.


Frequently Asked Questions

What is the best natural remedy for LPR?

The best natural remedy for LPR is a combination of a strict low acid diet and alkaline water at pH 8.8 or above. The diet stops pepsin from being reactivated by dietary acids. The alkaline water permanently deactivates pepsin already in the throat. A 2017 JAMA study found this dietary approach matched PPI therapy for symptom reduction in LPR patients — making it the most evidence-backed natural treatment available.

Can LPR be treated without medication?

Yes — for many people LPR can be significantly improved or resolved through diet and lifestyle alone. The low acid diet, alkaline water and the lifestyle changes described in this article are the foundation of natural LPR management. Gaviscon Advance is helpful and works through a natural alginate mechanism but is technically a medication. If symptoms are severe or persistent, it’s worth getting a proper assessment — consider a private consultation or speaking to a specialist.

Is chamomile tea good for LPR?

Yes — chamomile tea is one of the better herbal options for LPR. It has genuine anti-inflammatory properties, settles the stomach, and is a good evening drink for people who get hungry before bed and need something safe. Let it cool before drinking — very hot liquids can irritate an already inflamed throat. It won’t resolve LPR on its own but it’s a useful addition to the overall approach.

Is marshmallow root good for LPR?

Marshmallow root is the best tea option for throat soothing in LPR. Its mucilage content forms a protective coating over inflamed throat and oesophagus tissue, with confirmed anti-inflammatory effects in a 2025 systematic review. It doesn’t deactivate pepsin but it protects and soothes irritated tissue while it heals — which makes it genuinely useful alongside the main treatment approach.

Is apple cider vinegar good for LPR?

No — apple cider vinegar is not appropriate for LPR and can make it significantly worse. With a pH of around 2 to 3, ACV is highly acidic and will aggressively reactivate dormant pepsin in the throat. Despite its reputation as a natural remedy for acid reflux, it is counterproductive for LPR specifically and should be avoided.

How long does it take for natural LPR remedies to work?

Most people who apply the full combination — low acid diet, alkaline water, Gaviscon Advance, throat spray and the soothing teas — start to notice some improvement within 1 to 2 weeks. Meaningful symptom reduction typically occurs within 4 to 6 weeks. Full healing of the throat tissue can take several months, particularly if the condition has been active for a long time. Consistency matters far more than any individual remedy.


Conclusion

The most effective natural remedies for LPR are those that directly address pepsin — the low acid diet stops reactivation, alkaline water permanently deactivates it, and the alkaline throat spray targets what’s embedded in the throat tissue. Soothing teas like marshmallow root and chamomile are genuinely helpful additions during the healing phase. Slippery elm and DGL licorice are worth trying if you want to, but aren’t the priority spend for LPR specifically. And some commonly recommended natural remedies — apple cider vinegar, digestive enzymes, peppermint — actively make LPR worse and should be avoided entirely.


Related articles:


References

  1. Zalvan CH et al. (2017) “A Comparison of Alkaline Water and Mediterranean Diet vs Proton Pump Inhibition for Treatment of Laryngopharyngeal Reflux.” JAMA Otolaryngology-Head and Neck Surgery, 143(10):1023-1029. PMC5710251
  2. Koufman JA, Johnston N. (2012) “Potential benefits of pH 8.8 alkaline drinking water as an adjunct in the treatment of reflux disease.” Annals of Otology, Rhinology and Laryngology, 121(7):431-434. PubMed PMID 22844861
  3. Andrawes M et al. (2025) “Natural Products in the Management of Gastroesophageal Reflux Disease: Mechanisms, Efficacy, and Future Directions.” Nutrients, 17(6):1069. PMC11944625
  4. Raveendra KR et al. (2012) “An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia.” Evidence-Based Complementary and Alternative Medicine. PubMed PMID 22666280

David Gray

Content Researcher & Author

✓ Peer-Reviewed Research Medical Content

David Gray founded Wipeout Reflux to address a critical gap in reflux management. His research synthesizes over 100 peer-reviewed studies on laryngopharyngeal reflux (LPR), pepsin biology, and GERD pathophysiology. For LPR specifically—a condition most physicians misdiagnose—his work focuses on pepsin reactivation and why standard PPI therapy fails most patients. He develops evidence-based protocols targeting root causes of both LPR and GERD, integrating emerging research on sphincter dysfunction, dietary interventions, and newer clinical approaches. Wipeout Reflux represents practical application of clinical science for patients seeking real solutions.


32 thoughts on “Natural Remedies for LPR: What Actually Works (and What Doesn’t)”

  1. Hi. I was very interested to see another poster mention the feeling of a swollen gland on just one side. I have had minor reflux symptoms in the past but for 2 months had feeling of a swollen gland on one side with a hoarse voice. Ent put me on PPI 4 week trial and soon after that I started with sore throats and thick post nasal mucus. Could I have low stomach acid since PPI added new symptoms? Never have bitter acid taste in throat or mouth.
    Main question is the feeling of a swollen gland when I swallow only on ONE side a normal symptom? Thanks

    1. Hi,
      It’s possible you could have low stomach acid yes. Is it definitive though – absolutely not. I have heard of the swollen gland on one side, infact I have had it myself. While I am not certain I think it could be correlated or linked to your ears in that case too. I wouldn’t say it’s a common symptom but it does happen for certain people.

  2. I would just like to point out that a lot of people who have LPR also have low stomach acid (such as myself). I’m surprised you didn’t mention this since drinking alkaline water can cause further damage to those people.

    1. I mean there are a lot of potential causes to silent reflux. Some of which may be helpful for someone could perhaps irritate another person. Though generally speaking these suggestions help the vast majority of people with LPR.

    2. How do you know if you have low or high stomach acid – is there a specific test? I’ve been trying to get on top of LPR for 3 odd years now. I’ve had some success and most symptoms are almost gone but some still persist. I’ve tried a LOT of various things so now just wanting it to GO.

  3. Hi. The Slippery Elm lozenges you mention have been discontinued and are no longer available. Oh, I did find a small container for $60 on amazon. Any replacement suggestion? Thanks.

    1. I actually prefer to recommend something natural now, whether that is tea or some kinds of foods. Good food choices that are soothing are things like cucumber. celery, watermelon. What I actually like to do sometimes is make a juice with one or a mixture of these, not only is it refreshing but also really calms the stomach and digestive tract, celery in particular for me at least.

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